First, the nature of the nodule should be clear. If it is benign, even if it is large, it does not have to be treated. If it is malignant, the smaller the nodule, the better the treatment effect. 1. The nodule on the liver depends on the specific situation. If the patient is a benign disease such as liver cyst, liver hemangioma, even if it grows very large, it does not need to be treated. As long as the cyst is not on the surface, or the patient has no symptoms, even if it is 5~6cm or larger, it can continue to be observed; 2. If the nodules are liver cancer or other liver tumors, they should be actively treated regardless of size; 3. If the nodule is suspected to be caused by liver cancer, the smaller the treatment, the better the treatment effect.