Diane-35 can be used for oral contraception to treat moderate and severe acne (with or without seborrhea) and hirsutism caused by androgen sensitivity in women of childbearing age, including patients with polycystic ovary syndrome who need to treat these symptoms. The side effects mainly include nausea, abdominal pain, headache, mood change, breast pain, bleeding between menstruation, etc. Moreover, long-term use of Diane-35 may lead to water and sodium retention, which may lead to weight gain, endocrine disorders, skin elasticity loss, no gloss or long face spots. Therefore, it is necessary to take Diane-35 strictly under the guidance of doctors, and it cannot be abused privately.