Patients with long-term cough need to clarify the cause, whether it is cough caused by chronic bronchitis or bronchiectasis, whether there is pulmonary tuberculosis, whether it is cough variant asthma, and whether there is cough caused by esophageal reflux syndrome, and whether there is cough caused by esophageal reflux. It is recommended to be hospitalized and outpatient. After a clear diagnosis, appropriate treatment should be given, such as cough caused by chronic bronchitis. Cough treatment is recommended. It is symptomatic treatment such as relieving cough, resolving phlegm and relieving asthma. If it is cough caused by esophageal reflux, the patient should be given both cough relief and acid suppression treatment. If it is cough caused by postnasal drip syndrome, the patient should be treated in the otorhinolaryngology department, At the same time, the patients were given corresponding symptomatic treatment in otorhinolaryngology department. Therefore, for the treatment of long-term cough, symptomatic treatment and cause specific treatment should be given according to the etiology.