The symptoms of mycoplasma infection are diverse, and the clinical manifestations are related to the type of mycoplasma infection. There are many kinds of mycoplasmas. Human infections often include mycoplasma pneumoniae, ureaplasma urealyticum or mycoplasma genitalium. After mycoplasma invades the human body, if it infects the respiratory system, it is easy to cause symptoms of upper respiratory tract infection, such as fever, sore throat, chest pain, cough, and dyspnea. If infected with the genitourinary system, it will cause frequent urination, urgency, pain, even purulent secretion at the urethral orifice, and low back acid. No matter which part of the infection, sensitive antibiotics should be selected according to the course of treatment. After the inflammation recovers, the symptoms will gradually alleviate. Macrolide antibiotics such as azithromycin, erythromycin and roxithromycin are used to treat mycoplasma infection. There are also quinolone antibiotics, such as levofloxacin, moxifloxacin, gatifloxacin. The specific medication needs to be combined with the clinic, and the treatment should be guided by the regular urologist.