Indomethacin is mainly used for pain, swelling, and soft tissue contusion caused by arthritis. It also has antipyretic treatment, migraine, dysmenorrhea, surgery, and post-traumatic analgesia. At the same time, it also has many side effects, such as gastrointestinal reactions, indigestion, nausea, vomiting, stomachache, and acid reflux, which can easily cause gastric ulcer, bleeding, and gastric perforation. It can also cause nervous system reaction, which is manifested as headache, dizziness, anxiety, insomnia, and can cause mental and behavioral disorders in serious cases.