The reason why effervescent tablets can not be taken directly is that a large amount of gas will be produced in the process of decomposition when taken orally directly, which will lead to a large number of bubbles in the mouth, which is easy to cause damage to the stomach, or may lead to the formation of gas thrombosis. In serious cases, it may also block the respiratory tract, causing asphyxia. Also because effervescent tablets contain acid and alkali components, the acid components are mainly citric acid, malic acid, tartaric acid and other organic acids and inorganic acids, and the alkali components are sodium bicarbonate, sodium carbonate. The acid and base have a neutralization reaction to play its role, which is conducive to the rapid disintegration of drugs after melting in water. Therefore, the effervescent tablets must be put into warm water according to the instructions, and can only be taken after disintegration.