Compound clotrimazole cream contains hormone components. Compound clotrimazole cream is a mixture of clotrimazole and betamethasone. Betamethasone is a glucocorticoid. External use of hormone drugs can reduce inflammatory reactions and have an auxiliary treatment effect on skin infections caused by bacteria and fungi. However, corticosteroid drugs are not suitable for long-term use and are prone to cause adverse reactions. The most common adverse reactions are cortical hyperfunction, which is manifested as acne, full moon face, hypertension, edema, hyperglycemia, hyperlipidemia, aggravation of diabetes, osteoporosis, and mental disorder.