The main component of Kaisailu is glycerin, which is a kind of locally applied lubricating laxative. When used, the tip of the drug can be gently inserted into the rectum through the anus, and then the drug can be completely squeezed into the rectum. After the rectum is expanded to a certain extent, the defecation reflex will be enhanced, which can promote the excretion of feces. At the same time, glycerin in Kaisailu can play a certain role in lubrication, and can promote dry and hard stool to pass through the anus smoothly. However, long-term use of Kaisailu is not a good choice for constipation treatment. Because the occurrence of constipation is mostly due to bad living habits, diet structure and defecation habits, the fundamental solution to constipation is to actively adjust the lifestyle, diet structure, and establish good defecation habits. Repeated anal intubation can cause damage to the anus and rectum mucosa, and reduce the sensitivity of the rectum to defecation reflex, Causes increased constipation.