The International Pain Research Association defines neuropathic pain as pain triggered or caused by primary damage and dysfunction of the nervous system. It belongs to a kind of chronic pain, which is characterized by spontaneous pain, hyperalgesia, abnormal pain, abnormal sensation and other clinical symptoms; It is divided into peripheral neuropathic pain and central neuropathic pain. The main causes are physical mechanical injury, metabolism, or nutritional nerve changes, virus infection, neurotoxicity of drugs or radiotherapy, ischemic nerve damage, neurotransmitter dysfunction, etc. At present, drug therapy is mainly used, including pregabalin, gabapentin and kamasi.
