Cefoperazone sulbactam is a synthetic antibiotic. It has two components: cefoperazone and sulbactam. Cefoperazone is the third-generation cephalosporin, which plays a bactericidal role by inhibiting the synthesis of bacterial cell wall. Sulbactam not only has antibacterial activity against Neisseria gonorrhoeae and Acinetobacter, but also has irreversible inhibition on β - lactamase produced by drug-resistant strains. Therefore, the combination of cefoperazone and sulbactam has obvious synergistic antibacterial effect. It has significant synergistic bactericidal effect on influenza bacillus, haemophilus, Escherichia coli, Staphylococcus, Aerobacter, Proteus, Klebsiella, Enterobacter and other bacteria. Therefore, it can be used to treat upper respiratory tract infections, lower respiratory tract infections, urinary tract infections, abdominal cavity infections, endometrial infections, epidermal infections, soft tissue infections, meningitis and other infections caused by sensitive bacteria, and to prevent postoperative infections.
