The axillary lymph nodes mainly collect lymph from the upper part of the trunk, upper limbs, breast, chest, etc. Some tissue and organ infections, tumors, etc. will drain to the axillary, causing lymph node swelling and pain. The primary focus should be found and treated according to the accompanying symptoms. Generally speaking, painful lymph node enlargement is mostly caused by inflammatory bacterial infection, which can be treated with conventional penicillin or cephalosporins, or oral quinolones, such as levofloxacin, ciprofloxacin, etc. Generally, about two weeks after anti infection treatment, lymph nodes will be eliminated, lymph node volume will be reduced, pain will be reduced, and redness and swelling will be reduced.