People with high blood sugar suffer from chronic disease of local blood vessels and nerves due to poor blood circulation of their feet, especially when the toe is located at the end of the body, and the blood circulation is poor. With the progress of high blood sugar, the nerve sensation of the body ends weakens or disappears, and the self-protection mechanism is lost, for example, it is easy to cause damage. Once there is a small skin damage, it is extremely difficult to recover in a hyperglycemic environment, and it is easy to combine infection, and then toe rot occurs. The reason is that the blood sugar is too high, the control is poor, or the local blood supply is insufficient, there is infection, or the nutrition needed for the local wound tissue recovery is insufficient. To deal with this situation, we need to actively adjust the blood sugar to reach the standard, ensure the blood supply of the materials needed, and use drugs that nourish the peripheral nerves and protect blood vessels from oxidation. Under the guidance of the doctor, use the ointment for external use to remove decay and promote muscle regeneration, but remember to follow the doctor's advice. Ask a surgeon for local debridement to remove carrion and protect new granulation tissue. In short, this is the manifestation of diabetic foot, which should be actively treated and should not be ignored.