First of all, if constipation caused by organic diseases is excluded, such as functional constipation, a better drug at present is Linzeshu. In addition, you can also take some drugs containing lactulose, such as Dumac, Lido and Lilo, as well as intestinal probiotics and power promoting drugs, which can improve functional constipation. We do not recommend the use of aloe and some Chinese laxatives, because these drugs contain anthraquinone, which will make the intestinal mucosa black if taken frequently. We found that many patients took Chinese laxatives for a long time, and its intestinal mucosa showed leopard pattern changes under enteroscopy, also known as melanosis coli.