IGA nephropathy can vary from mild to severe. For patients with mild IGA nephropathy, more of the symptoms are recurrent gross hematuria or microscopic hematuria, and at the same time, there will be an increase in urinary protein to varying degrees. For patients with severe IGA nephropathy, in addition to the increase in urinary protein, there will often be a drop in blood pressure, or even a decline in renal function, with edema, Especially after getting up in the morning, eyelid edema and ankle edema of both lower limbs. Therefore, if ankle edema begins to appear in patients with IGA nephropathy, we must pay enough attention to it, seek medical advice in time, and determine the cause of edema. In general, the cause of ankle edema in patients with IGA nephropathy may be related to the decline of renal function, the reduction of glomerular filtration rate, and the retention of water and sodium, or it may be related to the loss of a large amount of urinary protein in patients with IGA nephropathy, which causes hypoalbuminemia in the body. Therefore, once the ankle edema begins in patients with IGA nephropathy, active treatment should be given, and corresponding treatment measures should be taken according to different causes.
