What's the difference between docetaxel and paclitaxel

Yangtze River and Yellow River Ask questions at 14:12:41, May 23, 2024
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First of all, the chemical properties of paclitaxel and docetaxel are similar, both of which are used in medical science to treat human tumor diseases, and the active substances of both drugs are derived from plants. The difference is that paclitaxel comes from the bark of Pacific yew, while docetaxel comes from the needles of European yew, and docetaxel is renewable. Through experimental analysis, the chemical structures of paclitaxel and docetaxel are different, and the chemical properties are greatly different due to the atomic chemical structure. The difference between docetaxel and paclitaxel is also reflected in the clinical treatment of diseases. First of all, these two drugs are both clinically used to treat certain cancer diseases, but paclitaxel will be resistant to a variety of cells with strong drug resistance, while docetaxel will not. In addition, their side effects are different. The use of docetaxel will cause hair loss and other phenomena, while the use of paclitaxel will cause allergic reactions or neurotoxicity.

Yangtze River and Yellow River 2024-05-27 10:42:29

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