High urine protein indicates the existence of kidney disease. Normal glomerular basement membrane can block protein filtration from the glomerular basement membrane in the human body. When in situ immune complexes or circulating immune complexes are deposited in the glomerulus, the charge barrier and mechanical barrier of the glomerular basement membrane are damaged, and protein can filter freely from the glomerular basement membrane, resulting in positive urinary protein. After the occurrence of positive urine protein, it is necessary to further check the 24-hour urine protein quantity, evaluate the amount of urine protein, improve the renal function examination, and relevant secondary renal disease indicators such as anti ENA antibodies, tumor indicators exclude secondary renal disease. If necessary, renal biopsy is performed to determine the renal pathology, and hormone or immunosuppressive drugs are used for treatment.
