How will gallstones not be operated on? If cholecystolithiasis occurs, it often causes pain, cholecystitis, and no operation will produce the following possibilities: 1. The cholecystolithiasis occurs when the cholecystolithiasis is embedded in the neck of the gallbladder, causing pain, cholecystitis, gallbladder necrosis, perforation, peritonitis, and aggravation of the condition. 2. Another possibility is that the gallbladder stone will not be operated. After a long time, the stone will move along the cystic duct to the common duct, forming the common duct stone. Common bile duct stones can cause acute cholangitis, acute pancreatitis, and easily endanger the life of patients. 3. However, there are also some patients with gallstones whose stones do not increase or move into the common bile duct to maintain the original status. This is a small number of patients, and most patients may become worse.