Patients with ankylosing spondylitis should go to the Rheumatology and Immunology Department. After going to the Rheumatology and Immunology Department, they need to further screen the HLA-B27 gene, check the ESR, C-reactive protein and other inflammatory indicators, and also do a sacroiliac joint CT. Through these tests, we can determine whether there is mandatory spondylitis. After a clear diagnosis, we need to use anti-inflammatory and pain relieving drugs, usually non steroidal pain relieving drugs, such as diclofenac sodium sustained-release tablets and some disease control drugs, such as sulfasalazine tablets, thalidomide tablets and other drugs. If the patient's economic conditions permit, and there is no hepatitis, tuberculosis or tumor disease, he can also choose biological agents for treatment. (The use of drugs needs to be carried out under the guidance of doctors)