The increase of urea nitrogen indicates that the patient may have kidney diseases, such as glomerulonephritis, interstitial nephritis, acute and chronic renal failure, etc. It needs to be analyzed in combination with the actual situation of the patient. Urea nitrogen and blood creatinine are important indicators of renal function. The level of indicators reflects renal function. If the indicators are found to be elevated, it is necessary to comprehensively analyze the pathological changes in combination with the patient's medical history, clinical symptoms and other inspection items. After the diagnosis of the above pathological changes, active treatment is required to correct renal function. In the course of treatment, urea nitrogen and blood creatinine need to be rechecked to clarify the effect of treatment and provide basis for the adjustment of treatment plan.