The medicine for ankylosing spondylitis includes three parts. The first type is anti-inflammatory and pain relieving drugs, which mainly refers to non steroidal pain relieving drugs. However, if the patient has pain in the peripheral large joints, such as the knee joint, he can also choose the local joint glucocorticoid puncture, which is commonly known as blocking. The second block is the choice of drugs for disease control, which mainly includes drugs such as sulfasalazine. Of course, the most effective treatment for ankylosing spondylitis is biological agents, but before using biological agents, diseases such as hepatitis, tuberculosis and tumor must be strictly excluded. (Drugs should be used under the guidance of doctors)