Rheumatism is generally caused by a variety of reasons, including genetic factors, infection factors, immune abnormalities in the body, etc. Rheumatism is not a simple disease, but a disease caused by many reasons. Heredity is one of the most important factors. There are abnormal genes in some families, and these abnormal genes will promote the occurrence of rheumatism. The occurrence of rheumatism in some patients is related to infection factors, and the most common is streptococcal infection. In addition, Helicobacter pylori, dysentery bacillus, etc., can also lead to the occurrence of rheumatic diseases. Endocrine disorders can also lead to rheumatic diseases, for example, the occurrence of systemic lupus erythematosus is related to the metabolic disorder of estrogen. Some patients may have immune responses in their bodies, and immune abnormalities appear under the stimulation of certain factors.