If women have pain at the urethral orifice, they need to observe whether there is secretion at the urethral orifice. If there is secretion at the urethral orifice, it is considered to be urethrostomitis. This situation is mostly caused by the bacteria infecting the urethral orifice. It is necessary to do a bacteria test of the secretion to identify the pathogen, and then do drug sensitivity tests according to the pathogen. Treatment with sensitive drugs will have a good therapeutic effect. Inflammation of female urethral orifice is related to the untimely hygiene of women, because female urethral orifice is very close to the vagina. If the vagina has secretions and is not cleaned in time, it may lead to bacteria breeding, or if women have some vaginitis, the secretions are also easy to pollute the urethral orifice, causing pain. Women in sexual life, sexual hygiene is not clean, may also lead to urethra stomatitis.