Pyelonephritis is divided into acute and chronic treatment plans. For acute pyelonephritis, it is recommended that patients use antibiotics intravenously. The choice of antibiotics can be second-generation antibiotics, second-generation cephalosporins, third-generation cephalosporins, or quinolones, such as levofloxacin. It is also suggested that patients with pyelonephritis should retain the bacteria culture of clean midstream urine and adjust antibiotics according to the results of bacteria culture. For patients with chronic pyelonephritis, this urinary tract infection may be repeated and may not heal. We recommend using multiple effective antibiotics. That is, cephalosporins may be used this month, and quinolones may be used next month. It is recommended to use furantoin at night to prevent recurrence. Pyelonephritis formulates his plan according to the patient's course of disease, and it is recommended to repeatedly check and clean the bacterial culture in the middle of the urine during the course of disease, and select antibiotics according to the results of bacterial culture and drug sensitivity.