Clinically, all severe colds refer to influenza. The common influenza viruses are A, B, C and D, and the common influenza viruses are A and B, which are easy to lead to severe influenza. In particular, children under the age of two, elderly and infirm patients, people with organ dysfunction or obese, pregnant and lying in women are high-risk groups. For patients with severe infection, we can consider using professional drugs for influenza treatment, such as commonly used neuraminidase inhibitors, such as Tamiflu and oseltamivir. Early application can achieve good results, and can also play a good role in the prevention of influenza. Hemagglutinin inhibitors can also be considered, but this drug has not yet been marketed in China. Clinically, for severe colds, early administration of neuraminidase inhibitors can achieve good results. Other treatments are judged by doctors. For example, if there is bacterial infection, corresponding medication should be used. For example, if there is pneumonia and poor respiratory function, oxygenation treatment may be required, mainly symptomatic support treatment.