The reaction time of taking misoprostol varies from person to person. Generally, when taking misoprostol for 3 to 4 hours, uterine contractions will start and embryos will be expelled. The other small part may not be ovulated until six hours, or even 12 hours later. So after taking medicine, everyone will have individual differences. General bleeding will be similar to the amount of menstrual bleeding in the past, accompanied by the discharge of the gestational sac. If there is too much bleeding, more than the amount of menstruation, and no pregnancy sac is discharged, it is necessary to perform uterine cleansing in time to reduce bleeding and prevent the occurrence of severe complications such as hemorrhagic anemia and hemorrhagic shock. It is recommended to observe the condition of uterine contraction and abdominal pain, the amount of vaginal bleeding and the discharge of pregnancy sac after taking the medicine, and find a doctor to check and confirm in time.