For patients with chronic nephritis, it is recommended to choose ACEI/ARB treatment, gradually increase the tolerable dose, try to control the urine protein below 0.5g per day, and delay the progress of renal function. After 3 to 6 months of optimized support treatment, patients whose urinary protein is still more than 1 gram per day and whose glomerular filtration rate is more than 50 ml can be treated with glucocorticoid. The patients with mild renal pathological changes can choose hormone or combined cytotoxic drugs, which often obtain better curative effect. If the renal pathological changes are serious, the curative effect is usually poor, especially in patients with a large amount of proteinuria and difficult to control, the renal damage continues to progress, and the prognosis is poor.