The question of what medicine to take for sore throat cannot be generalized. We need to make a comprehensive analysis based on the duration of the course of the disease, whether there are inducing factors, objective physical examination and laboratory auxiliary examination, and formulate the corresponding treatment plan after the differential diagnosis. If the duration of the disease is relatively short and you have a cold, you should consider that it is acute pharyngitis, which may be caused by viral infection, or it may be accompanied by bacterial infection. In terms of treatment, antiviral drugs or antibiotics should be used for anti-inflammatory treatment, and glucocorticoid should be used for detumescence, atomization, mouthwash and other symptomatic treatment. If the duration of the disease is relatively long, it is possible to consider reflux laryngitis caused by gastric acid reflux stimulation, or pharyngitis and pain caused by nasal rhinorrhea reflux. In this case, it is necessary to further improve the detailed examination of the specialty, clear diagnosis and symptomatic treatment.