The main manifestations of thyrotoxicosis are: 1. Hypermetabolic syndrome. The patients often have fatigue, weakness, fear of heat and sweat, wet skin, excessive food and hunger, and significant weight loss. 2、 Mental nervous system, restless, nervous, irritable, insomnia, lack of concentration, memory loss. 3、 Cardiovascular system, palpitations, shortness of breath, tachycardia, low heart sounds, high systolic pressure, low diastolic pressure, high pulse pressure, heart enlargement and heart rate failure. 4、 Digestive system, increased defecation frequency, severe cases may have hepatomegaly, abnormal liver function, and occasionally jaundice. 5、 The musculoskeletal system, mainly hyperthyroidism periodic paralysis, is common in Asian men aged 20 to 40 years old. The predisposing factors include strenuous exercise, high carbohydrate diet, insulin injection, etc. 6、 In the hematopoietic system, the ratio of peripheral blood lymphocytes and monocytes increased, but the total number of white blood cells decreased, which can be accompanied by thrombocytopenia. 7、 The reproductive system, female menstruation reduction or amenorrhea, male impotence, occasionally breast hyperplasia.