Depression and irritability can be treated with sertraline according to the doctor's advice. It is mainly caused by drinking for a long time. It can also be inherited if the patient's parents have depression. It is mainly due to depression, loss of interest, anxiety, cognitive decline and mental retardation. When it is found early, it is necessary to go to the psychiatric department of the hospital in time for mental examination. During the treatment, you can do some proper exercises, such as walking, jogging, and shadowboxing.