How to treat mycoplasma pneumoniae antibody positive patients needs to be determined according to the specific conditions of the patients. First of all, positive antibodies to Mycoplasma pneumoniae do not necessarily lead to Mycoplasma pneumoniae infection. Some studies have shown that some normal people can be positive antibodies to Mycoplasma pneumoniae, and these people do not need treatment. Secondly, mycoplasma pneumoniae antibody appeared 7 days after mycoplasma infection, peaked around 3 weeks, and turned negative for 12 to 16 weeks (different opinions, but all indicate that the duration is long). Therefore, mycoplasma pneumoniae antibody is positive, which may be that it has been infected with mycoplasma pneumoniae in the past, is recovering, or has recovered, which generally does not require treatment. The last case is the acute infection of Mycoplasma pneumoniae. Mycoplasma pneumoniae infection is a self limiting disease, and most patients can heal themselves without treatment. If the patient's body immunity is low and the general condition is poor, or the imaging and clinical symptoms indicate that the infection is serious, early and appropriate use of antibiotics can reduce the symptoms and shorten the course of disease. The first choice of antibiotics is macrolide antibiotics, such as azithromycin, roxithromycin, etc.