Allergic urticaria is mainly systemic medication. The first choice for treatment is antihistamine, among which the second generation H1 receptor antagonist is the most commonly used. The therapeutic effect is poor, and the first generation H1 receptor antagonist, glucocorticoid, adrenaline, thyroxine, leukotriene receptor antagonist, sulfapyridine, colchicine, hydroxychloroquine, dapsone, indomethacin, cyclosporin, intravenous immunoglobulin, thiazolidine, methotrexate, biological agents, etc. can be replaced or combined, and doxepine cream, calamine lotion Mint or camphor tincture, capsaicin cream, etc. Urticaria is a common skin, mucous membrane and vascular reactive disease, which is manifested by intermittent itchy wind masses. The center of the skin lesions can subside, and the appearance is circular or multi circular.