The urine routine examination of normal people shows that the kidney is basically normal if the urine protein is negative. If the urine routine examination shows that the urine protein is positive, it indicates that the kidney has pathological changes, which may be the pathological changes of the glomerulus, including the proliferation of mesangial cells, or the change of the basement membrane filtration barrier, or the slight damage of the renal tubules. If the urine routine test is positive, the urine protein should be rechecked again, because sometimes fever, strenuous exercise, and more protein intake can also lead to a transient positive urine protein, so the urine routine test is positive and the urine protein needs to be rechecked again. At the same time, it is better to do the determination of urinary microalbumin creatinine ratio, And quantitative determination of 24-hour urinary protein. If multiple reexaminations and different examination results indicate that there is proteinuria, it can be determined that there is a disease in the kidney. At this time, it is necessary to further go to the nephrology specialist clinic to do a series of examinations such as kidney B-ultrasound, blood sampling to check renal function, and ultrasound of renal arteries to determine whether there is a disease in the kidney. If necessary, renal puncture biopsy is required.