SLE is the abbreviation of systemic lupus erythematosus. Systemic lupus erythematosus is an autoimmune disease that tends to occur in young women. Systemic lupus erythematosus is characterized by multiple system and organ dysfunction, and multiple autoantibodies in the serum. In terms of clinical manifestations, patients with systemic lupus erythematosus often have symmetrical butterfly erythema, recurrent oral ulcer, photosensitivity, Raynaud's phenomenon, repeated swelling and pain of multiple joints, muscle pain or weakness. Lupus erythematosus patients will also show multiple organ dysfunction. Renal impairment will lead to proteinuria, hematuria, and even renal insufficiency. Hemolytic anemia, leukopenia or thrombocytopenia may occur when the blood system is damaged. The respiratory and circulatory systems are damaged, and patients often have multiple serous effusion, pulmonary hypertension, etc. The patient's nervous system, digestive system and endocrine system will also be affected. In terms of serological examination, patients with systemic lupus erythematosus were more positive for anti nuclear antibody, anti double stranded DNA antibody and anti nucleosome antibody.