Some patients with hyperthyroidism may feel uncomfortable at the neck. Because some patients with hyperthyroidism will experience neck thickening, according to the etiology of hyperthyroidism, the causes of hyperthyroidism are mainly divided into four categories. They are Graves disease, toxic nodular goiter, high function adenoma and other causes, such as pituitary hyperthyroidism. Among them, if the patient with toxic nodular goiter has more nodules and larger volume, it will increase the volume of the thyroid gland invisibly and make the neck of the patient thicker. In addition, high-powered adenomas may also have similar manifestations of toxic nodular goiter. Therefore, some hyperthyroidism patients will still cause neck discomfort.