Urticaria is a common skin disease, also known as wind pimple. It is a localized edema reaction due to the reactive expansion of small blood vessels and the increase of osmotic pressure of the skin mucosa caused by various reasons. Therefore, it is characterized by red or pale wind masses on the skin accompanied by severe itching. Adults have urticaria: first of all, we should actively find the cause and remove the incentives, such as dietary factors, environmental factors, drug factors, infection factors, etc; Secondly, drug treatment is needed to improve symptoms. Mild urticaria can be treated with oral antihistamines, such as loratadine, cetirizine, ebastine, mizolastine, etc. Some patients with acute urticaria will be accompanied by shock, laryngeal edema or dyspnea. At this time, it is necessary to actively rescue and systematically give glucocorticoids for treatment. If chronic urticaria is not good repeatedly, regular and long-term antihistamines should be taken for treatment, and immunosuppressants or biological agents can also be added.