Carpal tunnel syndrome is when the median nerve is compressed in the carpal tunnel, resulting in hand numbness. The drugs available are limited. There are two types of drugs available. One is neurotrophic drugs, the most commonly used is mecobalamin, and the other is anti-inflammatory and analgesic drugs, including diclofenac sodium, celecoxib, meloxicam, etc. Anti inflammatory and analgesic drugs are mainly used to relieve local pain and inflammatory reaction. In addition to taking drugs, they can also intramuscularly inject the neurotrophic drug cobalamin adenosine, which is better than oral drugs. If the symptoms of hand anesthesia are not alleviated after rest and oral or intramuscular injection of drugs, the nerve electromyography should be carried out as soon as possible to determine that the nerve compression site is in the carpal tunnel, and then the transverse carpal ligament of the hyperplasia and compression of the median nerve should be cut by surgery, while the median nerve should be given an adventitia release, which often can quickly relieve the numbness of the hand after surgery, The treatment effect is good.