We usually rely on the imaging examination of renal function and urinary system to check uremia. The main purpose of renal function examination is to observe urea and creatinine. If creatinine exceeds 707umol/L and urea exceeds 28mmol/L, it indicates that the detoxification ability of the kidney is greatly reduced. However, uremia cannot be diagnosed at this time, because some acute factors, such as taking a large number of nephrotoxic drugs in a short period of time, can also lead to an increase in creatinine, but this situation cannot be diagnosed as uremia. Uremia emphasizes the gradual development of chronic kidney disease. At this time, the imaging examination of the kidney is needed, and the most common is the color ultrasound or CT of the kidney. If the imaging examination shows that the volume of the kidney is significantly reduced or the renal cortex has become thinner, this situation indicates that it is developed from chronic kidney disease and can be diagnosed as uremia. Of course, other examinations need to be improved to clarify the specific causes of uremia. Some causes still need to be treated, such as systemic lupus erythematosus.