If patients with periodontitis need systemic medication, they can recommend several drugs: the first drug, which we use most, is called metronidazole. Metronidazole is relatively cheap but effective. It is an anti anaerobic drug, so it can achieve a better therapeutic effect for periodontitis. Generally, it should be taken orally 3 to 4 times a day, 200 mg each time, for 5 to 7 consecutive days. Of course, if the metronidazole reaction is severe in this kind of patients, then you can consider using other ones. Of course, other drugs may be tetracyclines, such as minocycline or tetracycline. Tetracycline is not available to pregnant women and children before the age of seven. Of course, it can also be used with amoxicillin. The side effects of amoxicillin are relatively small, and many patients can use it. The above scheme is only for reference. Please use the drug according to the drug description or the doctor's advice in a regular hospital.