Most patients with hyperthyroidism will have one to two degrees of neck swelling in the course of illness. The main reason for goiter is the increase in synthesis and secretion of thyroid hormone, which promotes the proliferation and hypertrophy of thyroid epithelial cells and makes the thyroid gland enlarged. Secondly, some thyroid antibodies, including globulin antibodies and microsomal antibodies, also promote thyroid tissue enlargement, which is caused by autoimmune diseases. In addition to neck enlargement, most hyperthyroidism patients also have hypermetabolic syndrome, which mainly includes panic, sweating, fear of heat, hyperappetite, increased stool frequency, arrhythmia, and exophthalmos. The thyroid hormone level and antibody level in blood examination were increased to varying degrees. After treatment, the neck of most patients may return to a relatively normal state. Neck enlargement In addition to hyperthyroidism, hypothyroidism, thyroid nodules, thyroid tumors may lead to neck enlargement.