Acne is a chronic inflammatory skin disease of the hair follicle sebaceous gland. Its onset is related to factors such as increased secretion of the sebaceous gland, excessive keratinization of the hair follicle sebaceous gland duct, infection of Propionibacterium acnes, and immune inflammatory reaction. In addition, the onset of some patients is also affected by genetic, immune, endocrine, emotional, diet, cosmetics and other factors. The treatment of acne needs to be selected according to the main skin lesions of acne and its severity grade. For mild patients and external drug treatment, vitamin A acids such as adapalene gel and tazarotene gel, antibiotics such as benzoyl peroxide, azelaic acid, fusidic acid cream and selenium disulfide can be selected.