The drugs taken for anal swelling are mainly based on different causes. In clinical practice, anal swelling mainly includes hemorrhoids, perianal infection, and even perianal abscess. For anal swelling caused by hemorrhoids, it is mainly to strictly control diet, avoid eating too greasy, spicy and irritating food, locally use 1:5000 potassium permanganate hip bath, and apply various hemorrhoid creams or hemorrhoid suppositories. Oral drugs mainly include detumescence drugs such as Diosmin tablets, which can relieve hemorrhoid symptoms. If it is perianal infection, anti infection treatment can be taken when there is no abscess. Oral medicine is more than second-generation cephalosporins, which can kill both gram-positive cocci and gram-negative bacilli. If an abscess is formed, the simple anti infection treatment is usually ineffective. It is necessary to cut and drain the abscess in time, and then strengthen the anti infection. The anti infection drugs are also more than second-generation cephalosporins. If necessary, they even need to be combined with anti anaerobic drugs, such as metronidazole.