The large fluctuation of blood pressure in hypertensive patients is mainly related to the following factors. First, emotional tension, excitement, tiredness, staying up late and other factors can lead to large fluctuation of blood pressure. Second, the use of antihypertensive drugs is inappropriate, especially the use of short acting drugs. Because of the short action time of each drug, it will lead to repeated fluctuations in blood pressure. After this situation occurs, the first thing to do is to start with lifestyle adjustment, low salt, low fat diet, smoking cessation and alcohol restriction, proper exercise to control weight, and then to maintain a healthy lifestyle, go to bed early and get up early, Avoid emotional tension and excitement. In the aspect of drug selection, you can choose antihypertensive drugs, long-term antihypertensive drugs, once a day, which can maintain the stability of blood pressure and avoid repeated fluctuations of blood pressure.