Patients with COPD usually take inhaled drugs as the main treatment, and can also take some drugs orally. Common drugs include tiotropium bromide, salmeterol, fluticasone, budesonide, formoterol, etc. These drugs are inhalation drugs, which are inhalation long-acting bronchodilators or inhalation long-acting bronchodilators combined with glucocorticoids. In addition, some oral drugs are also helpful for patients with COPD. For example, if patients with chronic obstructive pulmonary disease cough and expectoration are obvious, they can take carboxymethyl stane and N-acetylcysteine orally. These drugs can help patients expel sputum and reduce the number of acute exacerbations of chronic obstructive pulmonary disease. In addition, chronic obstructive pulmonary disease (COPD) with serious condition can also be treated with oral small dose of macrolide antibiotics and roflukast.