In general, detumescence drugs cannot be used for a long time. Because long-term use of detumescence drugs may lead to adverse reactions such as water electrolyte disorder in the body. The commonly used detumescent drugs in clinic are diuretics, such as spironolactone tablets, furosemide tablets, hydrochlorothiazide tablets, and injections, such as furosemide injection, tolathimide injection, etc. If patients have drug indications, detumescent drugs can be used for a short time. The key to edema is to find out the cause and make a clear diagnosis, and actively treat the primary disease, such as heart failure, liver function decline, kidney function decline, etc. At the same time, diuretics were given to improve heart, liver and kidney function. In addition, for the symptoms of redness, swelling, heat and pain caused by local infection, antibiotics are mainly given, and there is no indication for diuretics.