To check the function of renal tubules, laboratory tests of urine and blood as well as imaging examinations are required. Routine urine examination shows that if there are abnormalities in urine protein, tube type, specific gravity, renal tubular epithelial cells and other values, it indicates that renal tubules are damaged. If the damage of renal tubules is relatively minor, the amount of urinary protein will not be too large, and microalbumin in urine can also be detected. If there is leakage of small molecular protein, it indicates that the renal tubules are damaged. The most accurate is the detection of biochemical indicators. Through the detection of biochemical indicators, it can be clear whether there is acid-base balance disorder. In addition, relevant examinations of renal function and imaging are also needed to make comprehensive assessment and judgment, and then targeted treatment.