Urticaria is a localized edema reaction due to the expansion of small blood vessels and increased permeability of skin mucosa. It is easy to recur and has a long course of disease. There are several ways to treat urticaria: First, for urticaria with clear causes, avoid contacting with allergens again. Second, for patients with unexplained urticaria, antihistamines, such as loratadine, cetirizine, ebastine, and H2 receptor antagonists, such as cimetidine, ranitidine, can be used in combination. Third, for patients with severe urticaria, antibiotics and glucocorticoids can be added according to the white blood cells in the blood picture. For patients with severe respiratory and gastrointestinal symptoms, such as dyspnea, nausea and vomiting, they should go to the hospital for further examination and treatment in time to avoid delaying the condition.