Pregnant or lactating women need to take vitamin B supplements, especially vitamin B12 and folic acid. Lack of vitamin B12 and folic acid in pregnant or lactating women can lead to serious nerve damage or birth defects in the fetus or baby, so vitamin B family needs to be supplemented. People with certain diseases, such as celiac disease, cancer, Crohn's disease, alcoholism, hypothyroidism, anorexia, and people who have undergone weight loss surgery are prone to vitamin B deficiency. It is recommended to supplement vitamin B to correct or avoid defects. In addition, people who take drugs that can lead to vitamin B deficiency need to supplement vitamin B, such as proton pump inhibitors and other drugs to reduce gastric acid, which can reduce the absorption of vitamin B12. Long term use of metformin can reduce the levels of vitamin B12 and folic acid. Taking contraceptives consumes vitamin B2, vitamin B6, vitamin B12 and folic acid. Therefore, people taking the above drugs need to take vitamin B supplements.