Interstitial brain edema is mainly caused by the obstruction of cerebrospinal fluid return, such as left eardrum descending hemorrhage, thalamic hemorrhage, ventricular hemorrhage, etc., which will affect the normal return of cerebrospinal fluid. If cerebrospinal fluid cannot return, it will gather in the ventricle and cause edema. The cerebrospinal fluid flowing into the surrounding interstitium will form interstitial edema. In case of interstitial edema without specific drug treatment, the pressure of intracranial pressure should be measured first. If there is obvious increase of intracranial pressure, drainage of lumbar cistern or ventriculoperitoneal shunt can be performed to reduce intracranial pressure and reduce brain edema. The disease should be seen in the hospital at an early stage and checked and treated under the guidance of a specialist.