Gastrointestinal cold is a special type of upper respiratory infection, and drugs can be taken according to the condition and etiology. Patients often have symptoms of nausea, vomiting, even abdominal pain and diarrhea, so they can choose some drugs to protect gastrointestinal mucosa, such as taking probiotics properly, such as bifidobacteria quadruplex viable tablets, lactobacilli tablets. You can also take Chinese patent medicines with stomach strengthening and digestion effects, such as stomach strengthening and digestion tablets and spleen strengthening oral liquid. In addition, vitamin B6 can also be properly taken to achieve the effect of antiemesis. For etiological treatment, antibiotics such as penicillin, cephalosporins and other drugs should be taken in case of bacterial infection. If it is caused by virus infection, you can take ribavirin, oseltamivir and other drugs appropriately.