So far, the cause of depression is not very clear, but it is certain that biological factors, social and psychological factors, as well as environmental factors, are involved in the pathogenesis of depression. Biological factors mainly relate to heredity and the situation of brain neurotransmitters, as well as the situation of nerves, endocrine and nerve regeneration. The psychological predisposing factor closely related to depression is the personality of the patient before the disease, such as the temperament of January. Maybe you have heard of Lin Daiyu's temperament and Lin Chong's temperament before. You can know the temperament of the characters through evaluation. What kind of temperament is likely to cause depression? People who are prone to depression are mostly people with depressive temperament. In addition, life events that encounter emergency events in adulthood are also important trigger conditions that easily lead to specific clinical symptoms. Therefore, we should comprehensively evaluate the onset of depression from its personality, psychological, social and biological factors.